Dominggus Mandacan is an Indonesian politician who is the governor of West Papua, serving since February 2025 after his first term from 2017 to 2022.

[1][2] Surabaya Mayor Tri Rismaharini traveled to the province to help campaign for Mandacan and his running mate, Mohammad Lakotani, and the Mandacan-Lakotani ticket had the support of both the Indonesian Democratic Party of Struggle and the Nasdem Party.

[3] He was the son of Lodewijk Mandatjan, the leader of Arfak tribe, and alongside Barents Mandatjan, were early figures of Indonesian Nationalist in Papua who was involved in red-white flag raising ceremony in Borarsi, Manokwari, before switching side to support Papuan Independence.

During 1963-1969, He alongside Permenas Ferry Awom, former member of PVK, lead a group of early OPM waged a guerrilla warfare against Indonesian forces.

A police hospital, RS Bhayangkara Polda Papua Barat, was also named after him.