He was married to Magdalena Comparetti on 10 October 1700 in the church of San Andres de Panigaglia in La Spezia.

He travelled with his sister Micaela Pelliza Brignole, who married Manuel Duarte en Buenos Aires.

The Mayordomo of Buenos Aires was the person in charge of the administration of the local economy in colonial Argentina.

[6] In addition to carrying out police and militia tasks in the Río de la Plata,[7] Pelliza also engaged in trade and agriculture, as he owned several lots of land and properties in Buenos Aires.

He married her cousin Thomasa Vargas Machuca del Cerro Jurado y Correa de Sa on 1805.