Dominik Anton Cajetan Brentano (October 6, 1740 – June 2, 1797) was a Swiss publicist, Enlightenment theologian, and Bible translator.

He was born in Rapperswil on Lake Zurich, the twelfth child of the silk manufacturer and merchant Laurentius Brentano (1707–1746) and his wife Maria Francisca Rusconi, a native of Lucerne.

[3] Here and at the affiliated Collegio di Brera, Dominikus completed his studies with a doctorate in theology and was ordained priest in 1763 by Giuseppe Pozzobonelli, the Archbishop of Milan.

In accordance with family tradition, Dominikus took in his niece Marianne, the daughter of Franz Xaver Brentano, who died in 1775, and encouraged her education.

[5] He also took in another nephew, Heinrich Franz Ernst Brentano (1768–1831), who had also lost his father at an early age, and supported his theological studies in Freiburg.

[8] In the New Testament, Brentano initially relied on the Fulda Bible, the translation by the Jesuit Joseph Andreas Fleischütz published in 1778, until the middle of the Gospel of Matthew.