Giordano has played roles in work directed by Mauro Bolognini, Jean-Luc Godard, Neil Jordan, Ken McMullen, Nicolas Roeg, and Andrei Tarkovsky, amongst others.

After her studies, she continued to work on visual arts and photography, beginning her career as an assistant director for stage and film.

Giordano first appeared on screen in Mario Monicelli's Amici Miei - Atto II in 1982.

Giordano also played roles in such films as Jean-Luc Godard's Nouvelle Vague (1990) and Neil Jordan's Interview with the Vampire (1994).

[3] Giordano also collaborates with the online magazine Nova of the Italian newspaper Il Sole 24 Ore.