It is part of the municipal fairgrounds, and is one of the primary venues of the annual Feria Leon.

It is also used for circuses, lucha libre, motorsports, boxing, graduations, ice shows and other events.

[2] Among the many acts who have performed at Domo de la Feria have been: Paty Cantú, Rocio Durcal, Lupita D'Alessio, Vicente Fernandez, Joan Sebastian, Juan Gabriel, Maribel Guardia, Lucero, Gloria Trevi, Thalía, Paulina Rubio, Los Tigres del Norte, Lorena Herrera, Mana, Jenni Rivera, Banda del Recodo, Danna Paola, Aracely Arambula, Pepe Aguilar, WWE Live and many others.

This venue has also been the venue for sports such as Futsal, Female American Football, Boxing, Handball, Judo, Karate, Olympic Wrestling, Mixed Martial Arts, Taekwondo and Professional Wrestling with WWE, Lucha Libre AAA Worldwide, Consejo Mundial de Lucha Libre, and The Crash Lucha Libre.

It also hosted matches for the 2024 FIBA Under-17 Women's Basketball World Cup including the final phase.