Don't Toy with Me, Miss Nagatoro (Japanese: イジらないで、長瀞さん, Hepburn: Ijiranaide, Nagatoro-san) is a Japanese web manga series written and illustrated by Nanashi, also known as 774, about a high-schooler and art club member who is frequently annoyed by his junior Nagatoro, unaware of her real feelings for him.

Naoto Hachiouji, an introverted second-year student at Kazehaya High School, prefers to avoid social interactions and draw manga in his spare time.

However, first-year girl Hayase Nagatoro inadvertently discovers the manga, calls him her "Senpai", and teases him to the point of crying.

She starts frequenting the art club room where he hangs out, and continues to bully him for his timid personality and otaku interests, sometimes in a sexually suggestive fashion.

As she continues to push him to become more assertive, he slowly realizes he is falling in love with her, and gradually comes out of his shell and involves himself in her life.

Nagatoro takes part in a judo tournament and makes Senpai promise that if she defeats her rival, Orihara, he will give her a kiss.

So, Senpai makes a promise of his own: if he scores first at his mock university entrance exam, he will confess to Nagatoro.

After the rest of the year goes without problems, Senpai graduates from the school and moves to Tokyo, though he returns to celebrate Nagatoro's birthday.

Nanashi first posted early prototypes of what would become Don't Toy with Me, Miss Nagatoro on Pixiv between August 2011 and December 2015, with five issues total released during this period.

[17] Don't Toy with Me, Miss Nagatoro was serialized through Magazine Pocket, published by Kodansha, from November 1, 2017, to July 23, 2024.

A special edition was released in paperback with an included full-color booklet which put Senpai and Nagatoro in erotic situations.

The series was directed by Hirokazu Hanai at Telecom Animation Film, with Taku Kishimoto supervising scripts, Misaki Suzuki designing the characters, and Gin composing the music.

[77] Titled Don't Toy with Me, Miss Nagatoro 2nd Attack, the season is directed by Shinji Ushiro and produced by OLM, replacing Hanai and Telecom Animation Film.

[81] English dub voice actress Kimberley Anne Campbell recalled in an interview that she redid her audition to make Nagatoro sound more mean, and "turned on the brattiness and gremlin".