Set during the United States Prohibition era, the series follows Angelo Lagusa and his quest to seek revenge against the Vanetti family.

The story is set in the United States during the last years of Prohibition in 1932, where brewed liquor dominates the black market thanks to the Italian Mafia.

After seven years in hiding in the Midwest following the night of the murder, Angelo receives an anonymous letter from a friend of his father's, prompting him to return to Lawless and exact his revenge.

Under the name of Avilio Bruno, he begins to infiltrate the Vanetti clan by slowly befriending the Don's son, Nero.

When Vincenzo Vanetti immigrates to USA, due to the economic crisis, he dreams of building an empire that he can rule.

He was extremely loyal to his Don, which by the time they controlled all brothels, bars and black market of Lawless.

[6] The series was broadcast from premiered on 9 July to 1 October 2016 on TBS[7] and also aired on the Animeism programming block on MBS,[1][5] CBC and BS-TBS.

Angelo and Nero take a trip to see the Atlantic Ocean against a backdrop of warring families and a dying empire.