Donald Herbert Carlsen (October 15, 1926 – September 22, 2002) was an American right-handed pitcher in Major League Baseball for the Chicago Cubs and Pittsburgh Pirates.

Born in Chicago, Illinois, Carlsen was signed by the Cubs as an amateur free agent in 1944 at age 17.

He made his one and only appearance for Chicago on April 28, allowing 4 earned runs in just one inning of relief work as the Cubs lost 8–1 to Johnny Vander Meer and the Cincinnati Reds.

He earned his first major league win on August 19 against his former club, the Cubs, and won his second six days later against the Philadelphia Phillies.

In ten total innings, he allowed 12 earned runs on 20 hits and five walks, making his final appearance on May 24 before returning to the minors.