Donald Preston Fambrough (October 19, 1922 – September 3, 2011) was an American college football player and coach.

Fambrough played college football at Texas in 1941 and 1942 before serving in the United States Army Air Corps during World War II.

Fambrough remained involved in Kansas football leading up to his death, and would occasionally take part in team practices.

[2] Fambrough is known for his hatred of rival Missouri[3] and gave an annual anti-Missouri speech to the football team before each Border War game.

Fambrough died September 3, 2011, at his home in Lawrence, Kansas from head injuries sustained in a fall.