He produced Robert Johnson's only recordings, and as head of Columbia Records' country music division later worked with many leading country musicians including Bob Wills, Carl Smith, Flatt and Scruggs, Lefty Frizzell, Ray Price, Johnny Horton, Marty Robbins and Johnny Cash.

After Satherley's retirement in 1952, Law took over national responsibility for Columbia's country music division, initially recording mainly at Jim Beck's studio in Dallas.

Law's productions in the late 1950s and early 1960s included Johnny Horton's "The Battle of New Orleans", Marty Robbins' "El Paso", and Jimmy Dean's "Big Bad John", all of which topped the US pop chart and helped bring country music to a wider audience.

[4][7] A son, Don Law Jr., became a music promoter in the Boston area, selling his company to SFX Entertainment in 1988 for $80 million.

[9] The season 2 episode 6 of the NBC series Timeless, "King of The Delta Blues", features Don Law, who is portrayed by Gavin Stenhouse.