He played the starring role of Sean Finnerty on the sitcom Grounded for Life (2001–2005), and Detective Harvey Bullock on the DC Comics adaptation Gotham (2014–2019).

He is also known for playing flight nurse Chuck Martin on ER (2003–2005), Lee Toric on Sons of Anarchy (2012–2013), Horik on Vikings (2013–2014), and the recurring role of Lt. (later Captain) Declan Murphy on Law & Order: Special Victims Unit (2014–2015).

Logue's film work includes roles in Sneakers (1992), Gettysburg (1993), Little Women (1994), Jerry Maguire (1996), Blade (1998), The Patriot (2000), American Splendor (2003), Zodiac (2007), The Cloverfield Paradox (2018), and Resident Evil: Welcome to Raccoon City (2021).

[3][4] His parents were Carmelite missionaries,[5] and the family moved from Ireland to Canada to Boston and elsewhere before settling in Calexico, California, in the state's Imperial Valley.

When I was there, auditioning for the role in front of Ben Kingsley and Robert Redford and getting nods of approval, it provided validation to my efforts.

Logue's portrayal as the lead in The Tao of Steve won him a Special Grand Jury Prize for best actor at the 2000 Sundance Film Festival, and was noticed by ER producer John Wells, who cast Logue in several episodes as Chuck Martin, a nurse Dr. Susan Lewis marries one weekend in Las Vegas on a whim, and later has a child with.

In December 2005, Logue had a pilot development deal for a new situation comedy on ABC television, originally titled I Want to Rob Mick Jagger.

Logue had appeared as Phil Stubbs in the original pilot for the NBC show Ed, but dropped out to star in the sitcom Grounded for Life.

The first two and a half seasons of Grounded for Life were telecast on the Fox network; thereafter, the show moved to The WB for the remainder of its run.

Logue also appeared in NBC's The Dennis, in 2005, about a former child prodigy whose parents kick him out of the house and into the real world.

After the show's cancellation, a frustrated Logue briefly left acting for truck-driving, according to his friend and fellow actor W. Earl Brown.

[14] Logue starred as the main character in Theory of a Deadman's music video for the song "Lowlife", off their 2011 release The Truth Is....

[15] From 2014 to the show's conclusion in 2019, he portrayed Harvey Bullock in the police procedural series Gotham, based on the DC Comics Batman franchise.