After playing college football for Alcorn State University, Driver was picked by Green Bay in the seventh round of the 1999 NFL draft.

[1] Donald had a tough childhood living out of a U-Haul truck for a period of time during his early teens, after a collection agency confiscated his family's possessions.

Donald spent multiple nights in motel rooms that his mother had purchased with food stamps.

He was a Texas All-State honorable mention in football, where he played at the wide receiver, defensive back, and kickoff return positions.

[2] Driver attended Alcorn State University in Mississippi, where he lettered in both football and track & field.

He competed for the Alcorn State Braves track team, where he excelled in the high jump and earned all-conference honors his senior year.

Driver was selected by the Green Bay Packers in the seventh round of the 1999 NFL draft with the 213th overall pick.

[9] On December 16, 2007, during a 33–14 victory over the St. Louis Rams, veteran Green Bay quarterback Brett Favre broke Dan Marino's all-time record mark of 61,361 career passing yards.

[11] In the NFC Championship game on January 20, 2008, against the New York Giants, Driver had the longest play in the playoffs of the Packers' franchise history with a 90-yard touchdown catch from Favre.

Driver finally broke the Packers' all-time receiving yardage record on September 18, 2011, against the Carolina Panthers after he caught a 10-yard pass from Aaron Rodgers, surpassing James Lofton.

[14] Out with an ankle sprain, Driver returned to the game in the end for the final plays as the Packers went on to beat the Pittsburgh Steelers 31–25.

It was held in the Lambeau Field Atrium with comments made by Mark Murphy, Ted Thompson, Mike McCarthy, and Driver.

He previously served as host to the annual Offense vs. Defense softball game featuring members of the Green Bay Packers.

As a well-known athlete in the state of Wisconsin, Driver has been featured in marketing campaigns for companies such as McDonald's, AirTran Airways, Kwik Trip, Goodwill, Jani-King and Time Warner Cable.

The books are based on Driver's bedtime storytelling to his three children, and are sold statewide in Wisconsin through bookstores, participating Goodwill locations, the Packer Pro Shop and on his website.

In the Fall of 2013, Driver released his official memoir, Driven, which included many personal stories about both his childhood and career with the Packers that he had never shared before and it made the New York Best Seller list.

[27] In the Summer of 2017, Driver released a health and fitness book, The 3D Body Revolution: The Ultimate Workout + Nutrition Blueprint to Get Healthy and Lean, which featured 25 recipes and 36 exercises illustrated with clear step-by-step photos.

[30] He operates a nonprofit called the Donald Driver Foundation in both Wisconsin and Texas and serves as the current cultural ambassador for Milwaukee's Marcus Center for the Performing Arts, in addition to business ventures.