Donald Masike'Vanua Kalpokas (23 August 1943 – 20 March 2019) was a Vanuatuan politician and diplomat who twice served as Prime Minister of Vanuatu.

On 6 September 1991, Kalpokas and other members of the Vanua'aku Pati defected from Lini's government and supported a no-confidence vote against him.

The elections resulted in the opposition Union of Moderate Parties taking control of the government, and Kalpokas left office on 16 December 1991.

The government collapsed in November 1999 when Kalpokas resigned as prime minister to prevent a no-confidence vote.

In August 2004, he was a candidate to become President of Vanuatu, and received 26 votes in the first round but then withdrew as it became clear that he would not be able to gain enough support.