As of the 2011 census, Donji Humac has a population of 177[3] – far below its height at the beginning of the 20th century of more than 500 people, before several waves of emigration depopulated the settlement.

Besides stone, the main sources of income have traditionally been wine, olives, cherries, sheep husbandry, hunting and, more recently, tourism.

In medieval times, most of the population of Brač lived inland, as the coast was too dangerous due to pirate and other attacks.

Cultural objects dug out from the cave of Kopačina, 1 kilometre (0.62 mi) to the north-west of Donji Humac, indicate human habitation since the Stone Age.

It was previously thought that the cave was continuously inhabited from the late Upper Paleolithic through the Mesolithic until the Bronze Age, i.e. from the 8th to the 3rd millennium BC.

The parish church of Saint Fabian and Sebastian is on the top of Donji Humac and dominates the view on the hill with its widely visible Baroque bell tower.

The Baroque bell tower and the two side ships of the church were added at that time, built by Ignac Macanović from Trogir.

The church hosts a fresco of Christ sitting on his throne between his mother and St John the Baptist, dating from the 13th century.

According to legend, every year on January 20, the day of St Fabian and Sebastian, dew would fall on the fresco, which led to many pilgrims coming to Donji Humac.

Today the annual feast of Saint Ana includes a large celebration and the blessing of motor vehicles.

The pre-Romanesque church of Saint Elias is located about 800 metres (870 yd) to the west of Donji Humac, and dates to the 10th century.

Saint Andrew, north east of the town, was built in the 13th or 14th century, on top of Roman ancient ruins.

People from Donji Humac have moved to Antofagasta in Chile, Perth in Australia, Auckland in New Zealand, the United States and later also Germany.