She released her debut album Donna in 1991 at the age of 14, featuring an original single "Kapag Tumibok ang Puso" and cover of Boy Mondragon's song "Rain".
She released Kurot sa Puso in early 1993 and later that year starred in the movie Kadenang Bulaklak alongside Vina Morales, Ana Roces, Angelu de Leon and Nida Blanca.
That same year that she starred in another drama produced by Viva, Pangako Ng Kahapon, together with Agot Isidro, Alice Dixson and Charito Solis.
In 1995, the Viva Entertainment Group gave Cruz a lead role in the soap opera Villa Quintana, opposite actor Keempee de Leon.
Habang May Buhay was top-billed by Cruz, Ian de Leon, Candy Pangilinan and veteran actress Hilda Koronel.
She also starred alongside Bong Revilla and Nanette Medved in the action romantic-comedy movie, Pag-Ibig Ko sa Iyo'y Totoo.
Cruz's last project before her marriage in September 1998 was in the tv series Growing Up where she had a supporting role to actress Angelu de Leon.
Cruz released her final album under Viva Records in 1999, entitled "Hulog ng Langit", which focused on love songs and lullabies.
At age 22, she gave birth to a daughter and released "Ikaw Pala 'Yon" her final single under her then-current contract with Viva Entertainment Group.
In 2001, Viva Records released Donna Cruz Sings Her Greatest Hits and in November of that year, performed at the Philippine Advertising Congress Awards in Cebu.