She went to the University of Maryland, College Park for doctoral study in physics, and completed her Ph.D. there in 1993.
[2] Her dissertation, A-Dependence of Photoproduced Jets and Comparison with Hadroproduction, was jointly supervised by Chia-Cheh Chang and Harry D. Holmgren, based on research at Fermilab.
[3] She became a postdoctoral researcher on the NuTeV experiment at Fermilab from 1993 to 1995, when she took a faculty position at Kansas State University.
[3] Naples has been part of experimental physics collaborations including NuTeV, NuMI, and COSMOS at Fermilab,[2][4] the NOvA[5] and MicroBooNE[6] neutrino oscillation experiments at Fermilab, and the Deep Underground Neutrino Experiment.
[7] Naples was elected as a Fellow of the American Physical Society (APS) in 2018, after a nomination from the APS Division of Particles and Fields, "for advances in the techniques of flux and cross-section determinations in the current and upcoming generation of accelerator-based neutrino experiments and fundamental contributions to neutrino event generators".