This was followed by the one-shot 2099 Special: The World of Doom (May 1995) with creator profiles and background articles and a 10-page fictional prose piece, "The Code of Citizen Conduct of the United States.

Doom confronts the new dictator of the nation, but is quickly defeated by Wylde's superior technology — his armor depleted of energy and destroyed, and his face is scarred.

With the aid of a brilliant Pixel employee he liberates from corporate enslavement named Dr. Celia Quinones, Doom creates a new, far more advanced and powerful suit of silver, blue cloaked armor capable of competing with Wylde's futuristic technology, in addition to performing neurocybersurgery on him.

[3] Alongside his few Zefiro allies, and with the use of the tritonium he has seized, Doom is able to defeat and destroy Wylde and regain control of his homeland to once again become Monarch of Latveria, ruling once more from a rebuilt Castle Doom, built "as a bridge between the village of Antikva and the metropolis of Gojradia" (apparently an expanded and advanced Doomstadt) once again.

[5] Doom travels into Cyberspace alongside Wire; there he battles Fever, the Virtual Reality Fantastic Four, Catscan, Haze, Paloma, and Duke Stratosphere.

Doom would later in the series recall the end of the "Age of Heroes", killing Reed Richards, growing old, and some vague memories of a war.

Despite this, he successfully introduces an addictive crab venom to his country, leading the populace to develop an immunity to the necrotoxin in an effort to save his people in the future.

He returned to 2099, to find Fortune and about 50% of the population of Latveria alive, due to the genetic immunity, though many Latverians had been mutated into humanoid creatures dubbed "mutalocos".

In reality Doom has been experimenting on humans, with the help of Xina Kwan, former lover of Miguel O'Hara, to find a way of purging the Techno Organic Virus.

He claims that he had always intended to allow the Phalanx to find Nostromo, as the techno organic growth has purged his country of outside influences and the ravages of the past century.

As reality begins to unravel around him, Doom is rescued by Kang the Conqueror, who recruits him as part of a larger plot against the Apocalypse Twins.

[15] After his defeat by Tyger Wylde, Doom underwent special surgery: nanotechnology was neuro-cybernetically added to the nervous system, speeding up those motor responses, allowing him to interface directly with any technology and heal himself from serious injuries.

Doom possesses extensive knowledge of all sciences, as well as is an expert in robotics, trans-Einsteinian physics, genetic engineering, military technology, chronophysics, biochemistry, and other fields.

[16] Doom wears an adamantium-lanxide laced armor over cybermesh circuitry, enabling tactile interface with nanoids in his brain and bloodstream that he designed with the help from Celia Quinones.

[21] An apparently immortal via body-hopping Victor Von Doom appears in Marvel Knights: 2099 that features an alternate take on the 2099 universe.

Doom appears in Marvel Knights 2099: Black Panther 2099, where aged and dying, Doom, seemingly employing the mind transferral ability he learned from the Ovoids, seizes the body of his current major domo Lucien in an apparently ongoing program implemented to ensure his continued survival.

Seizing opportunity, the rejuvenated Doom leads a Doombot invasion of Wakanda, which dominates the country for months, until a young council member named K'Shamba fights back.

[22] In a version of 2099 that was dominated by Ultron, Doom was shown to be an inmate at Hellrock Prison and is found in his cell by a time-displaced Dagger.