Dorotheos II (Greek: Δωρόθεος Βʹ) was the second metropolitan bishop of Trebizond under Ottoman rule.
Pankratios had been appointed, after such a long interregnum, to calm the anti-Ottoman agitation among the Christians of the Pontus region around Trebizond.
This agitation was particularly dangerous as it was encouraged by the neighbouring Aq Qoyunlu sultan Uzun Hassan, who was linked through family ties with the former imperial house of Trebizond and backed the designs of a scion of that house, Alexios Komnenos.
In order to counteract the threat of a rebellion, the Ottoman Sultan elevated the Trapezuntine Symeon I to Patriarch of Constantinople, and the latter immediately appointed Pankratios to the metropolitan throne of Trebizond.
It appears, however, that Pankratios was unable to calm the situation, or that he may have himself been actively involved in stirring up discontent, and after a few months the Sultan demanded his resignation.