Dorothy was born June 7, 1921, in New York City at St. Vincent's Hospital to Juanita Jennings, and was adopted by Babe and Helen Ruth (née Woodford).
Babe Ruth also somehow convinced Dorothy's biological mother to allow him to adopt their daughter, so that she could be raised with him and (a possibly unsuspecting) Helen.
After Helen's death, Dorothy lived with her father and Claire Merritt Ruth, whom he married in April 1929.
Dorothy's marriage to Sullivan also produced two daughters, Genevieve Herrlein and Ellen Ruth Hourigan (1943-2017), before the union ended in 1945.
Three children were born of this second marriage: Donna Analovitch, Richard Pirone (1950–2001), and Linda Ruth Tosetti (b.