Douglas Walgren (born December 28, 1940) is an American attorney and politician who served as a Democratic member of the U.S. House of Representatives from Pennsylvania from 1977 to 1991.

Walgren was born in Rochester, New York, and grew up in Mount Lebanon, Pennsylvania.

While at Stanford, he roomed off-campus with Dr. K. Barry Sharpless, who went on to be awarded the Nobel Prize for his work in chemistry.

He served as corporate counsel for Behavioral Research Laboratories, Inc. in Palo Alto, California, from 1973 to 1975.

Walgren was defeated by Rick Santorum, who, four years later, was elected Pennsylvania's junior United States senator.