Douglassia enae is a species of sea snail, a marine gastropod mollusk in the family Drilliidae.

The postnuclear whorls are marked by strong axial ribs that almost form cusps at the anterior termination of the posterior sinal region.

In addition to the axial ribs the whorls are marked by rather strong incremental lines that have a decidedly sigmoid curve, being retractively slanting at the posterior sinal region and protractively anterior to this.

The aperture is moderately large and rather broad, decidedly channeled posteriorly and anteriorly with a feeble stromboid notch.

[3] This species occurs in the demersal zone of the Caribbean Sea off Puerto Rico at depths between 73 m and 146 m; off Barbados and Guadeloupe; off Brazil.