He has appeared in the films Ever After (1998), Mission: Impossible 2 (2000), Enigma (2001), Ripley's Game (2002), Hitman (2007), and My Week with Marilyn (2011).

Scott began his acting career in national theatre, television, and puppet shows.

He was cast to play Wolverine in the feature film version of X-Men, but Mission: Impossible 2 went over schedule, and he was injured in a motorbike accident while shooting the chase scene.

[2][3] After the 2002 release of Die Another Day, Scott was a candidate to replace Pierce Brosnan as James Bond.

[4] Despite the numerous reports that Eon Productions was leaning towards naming Scott as the new Bond in the 007 adventure Casino Royale, the role eventually went to Daniel Craig.

[7] In March 2016, Scott became the voice of Orby in adverts for the oil and gas company BP.

[8] In April 2016, Scott appeared in the second season of Fear the Walking Dead as Thomas Abigail, Victor Strand's business partner and lover.

[9] In 2019, Scott joined the CW series Batwoman as Jacob Kane, the title character's father, set in the Arrowverse.