The institute offers MBBS, Bachelor of Science in Nursing BSN, DM, MCh, MD and Ph.D. degrees.

After its establishment in 2006, in 2012 it got Medical Council of India's approval to start post graduate and higher degree courses.

In 2015, Government of Uttar Pradesh start upgrading it into an State university by passing Dr. Ram Manohar Lohia Institute of Medical Sciences Act 2015 in assembly.

But after not getting approval from Governor of Uttar Pradesh for Dr. Ram Manohar Lohia Institute of Medical Sciences Act 2015, the cabinet in 2018 included suggestions given by governor and again started the process by preparing an amendment act.

[4][5] This time the act was approved by Governor of Uttar Pradesh and was notified on 12 September 2018.