The show has cameo appearances by famous characters (or in some cases, clones to avoid infringing copyright) from all across the animated spectrum.

In keeping with the various animation styles for the characters, Wooldoor and Toot have four fingers on each hand, whereas Clara, Foxxy, Hero and Xandir have five.

[5] In March 2007, it was announced that creators Dave Jeser and Matt Silverstein had left Comedy Central, and later created DJ & the Fro for their sister channel MTV in 2009, and eventually signed a two-year contract with 20th Century Fox Television to create new series and/or work on the studio's existing shows.

Since cancellation, the show has partial rotation late-nights, and airs uncensored on Comedy Central's Secret Stash and on Logo.

In response to the cancellation, the official page of Drawn Together in Myspace had suggested the fans call Comedy Central and convince them to make a new season.

The humor is largely morbid and satirical in nature, its primary focus being the mockery of stereotypes and the casual exploration of taboo subject matter, such as masturbation, paraphilia, kink, homosexuality or gay marriage, abortion, rape, incest, pedophilia, menstruation, spousal abuse, racism, homophobia, xenophobia, antisemitism, necrophilia, terrorism, graphic violence and death.

Sincere feelings the characters are forced to experience (and comic disregard thereof) seem to add integrity to the plot and imbue every episode with a genuine moral message, made more efficient by constant spoofing of moral message clichés like "character X has learned a valuable lesson".

Comedy Central's original tagline for the show was "Find out what happens when cartoon characters stop being polite... and start making out in hot tubs", referring to Clara and Foxxy's kiss in the pilot episode.

The aforementioned hot tub kiss is considered one of the show's defining images; Comedy Central based nearly all of its first-season promotional material for Drawn Together on it.

As Jess Harnell states in the DVD commentary for "Hot Tub", "Most of the racism on the show is coming from people who are so obviously stupid about it; it really isn't that threatening".

Only two episodes ("Lost in Parking Space, Part One" and "Nipple Ring-Ring Goes to Foster Care") do not feature a musical performance.

Plots and gags are often used that do not make any type of internal sense, but are used as one-off jokes, as when Foxxy, who is in her twenties, is said to have a teenage grandson.

Drawn Together features an ensemble cast of veteran voice actors (Tara Strong, Cree Summer, Jess Harnell, Adam Carolla, and James Arnold Taylor) and newcomers to the field (Abbey McBride and Jack Plotnick).

Principal cast member Tara Strong has stated that she deeply loves the show, as it was such a departure from the family-friendly productions that she was used to working on at the time.

[7] Originally, Xandir was to have been played by Nat Faxon, but he was fired following the first table read because the network felt his portrayal of the character was too stereotypically gay.

In the DVD commentary for "Hot Tub", Tara Strong jokes that this is because the show does not have a lot of money to pay guest stars.

USA Today deemed Drawn Together "the smutty offspring of Real World and Superfriends", stating that the pilot pushed the limits of taste, being overpowered by violence, sex, and disgusting subject matter.

Toot's cutting was praised as a good parody of self-harm presented on reality shows, but Spanky's flatulence was considered more disgusting than humorous.

Some reviewers called Drawn Together a "bizarre and highly entertaining series" which has a unique style of humor and "level of self-parody.

Special features include audio commentary on select episodes by creators Dave Jeser and Matt Silverstein along with assorted cast and crew members, in addition to deleted scenes and karaoke/sing-along versions of the show's songs.

Getting at least 11 of the 19 questions correct unlocks a hidden feature, a prank phone call by Jeser and Silverstein to their agent regarding the royalties they are to receive for the DVD audio commentaries.

The censored broadcast cuts of the episodes have never been made available on DVD or any other physical media, but they are available on Amazon.com's streaming service, with the original music.