The album's success continued with the follow-up singles "Physical", "Break My Heart", and "Levitating", with the latter topping the Billboard year-end Hot 100 chart of 2021 and receiving a Recording Industry Association of America (RIAA) Diamond certification in the US.

Lipa subsequently scored her third and fourth UK number-one singles with the 2021 Elton John duet "Cold Heart (Pnau remix)" and "Dance the Night" from the soundtrack of the film Barbie (2023), wherein she also made her acting debut.

[15][16][11] Her father continued to play music at home, including his own compositions and songs of artists such as David Bowie, Bob Dylan, Radiohead, Sting, the Police, and Stereophonics.

[3][28] In 2013, Lipa signed a contract with Tap Management, directed by Ben Mawson and Ed Millett, while working as a waitress in a cocktail bar.

[51] In January 2017, Lipa won the EBBA Public Choice Award,[52] and released the single "Scared to Be Lonely", a collaboration with Martin Garrix, reaching number 14 in the UK.

[72] It was reported that Lipa would be releasing collaborations with other artists coming out later in 2018, such as one with Mark Ronson and Diplo's newly formed superduo Silk City.

[84] Following the release of its lead single "Don't Start Now", Lipa's second album, Future Nostalgia, and its accompanying tour were announced in December 2019.

[113] On 27 November, Lipa performed in a livestream concert titled Studio 2054, where she sang various songs from Future Nostalgia, a new unreleased track with FKA Twigs, as well as some previous singles such as "New Rules", "One Kiss" and "Electricity".

[123] On 1 March 2022, reggae band Artikal Sound System filed a suit against Lipa and her label Warner Records alleging copyright infringement, asserting similarities between "Levitating" and their 2017 song "Live Your Life".

[125] A second suit by songwriters L. Russell Brown and Sandy Linzer claimed that "Levitating" infringed on their 1979 disco song "Wiggle and Giggle All Night".

She had spent part of her childhood in London and remembered her mother talking to her in a Pepe Jeans store in Portobello Road;[198] the collection included chain mail dresses, "casual" denim outfits and garments based on Lipa's "style" released in September 2019.

[233] She designed her outfit at the 63rd Annual Grammy Awards red carpet featuring a dress in collaboration with the brand Versace inspired by the Aurora Borealis.

[274] Her second studio album Future Nostalgia (2020) was inspired by artists that she listened to during her teens, including Gwen Stefani, Madonna, Moloko, Blondie and Outkast.

A YouTube comment on her performance of "New Rules" at the 2018 BRIT Awards saying "I love her lack of energy, go girl give us nothing" became an internet meme, subjecting Lipa to ridicule.

[284] She was included in Time's 100 Next list on future 100 world's most influential people by Australian singer Kylie Minogue who in her review called Lipa a "shining star".

Due to her ongoing Radical Optimism tour, Dua accepted the award via a pre-recorded video message, thanking fans for their support and expressing her gratitude.

[295] On 12 February 2018, she raised a rainbow flag while performing her song "Be the One" in a presentation at the Hollywood Palladium in Los Angeles as part of The Self-Titled tour.

[300] In September 2018, some fans were removed by security from a Lipa concert in the National Exhibition and Convention Center of Shanghai for allegedly waving rainbow flags, despite homosexuality being decriminalised in China in 1997.

[302] In November 2018, Lipa expressed dissatisfaction over the withdrawal of the United Kingdom from the European Union due to Brexit because according to her personal experience "no refugee leaves their country without having to.

[305] She participated in a short film for an initiative called "Global Feminism", directed by Annie Lennox's The Circle in association with Apple Music and released on 7 March 2019 ahead of International Women's Day.

[309][310] In July 2020, she signed an open letter to the UK government, being received by the then Minister for Women and Equalities, Liz Truss, to request the banning of conversion therapy.

[327] In May 2021, after expressing solidarity for the death of Palestinian civilians due to the Israel–Palestine crisis, Lipa criticised The New York Times for publishing an advertisement characterising her, along with Bella and Gigi Hadid, as antisemitic.

In response, Lipa wrote that it was an "honor and a privilege to be able to represent my country all over the world" and that she supports the right of Kosovans "to visa liberalization, freedom to travel and to dream big".

[336][337] She and her father, Dukagjin, co-created the Sunny Hill Foundation in 2016 to raise funds to help people in Kosovo experiencing financial difficulties.

[347] She asked for a better mental health care for artists in creative industries, as she was "shocked" to read that "suicide rates amongst women working in the arts are almost 70% higher than in the world population".

[349][350] To raise funds she co-released a limited edition line of t-shirts called "Pray for Albania" in collaboration with Albanian fashion designers.

[351][352] On 15 March 2020, she asked her fans to make donations to the UNHCR agency to deal with COVID-19 pandemic because refugees are "the most vulnerable on this planet" and they "often live in crowded places" with "limited health services".

[359] She was part of the charity supergroup Live Lounge Allstars in which each member recorded and filmed their contribution to the song from their respective households to encourage social distancing in which profits from the single would primarily go to Children in Need and Comic Relief, as well as COVID-19 Solidarity Response Fund.

[362] She was part of an initiative organised by Belgian singer Angèle and KickCancer Foundation to fund research against childhood cancer, and it was about a charity raffle in which Lipa offered a manuscript of her song "Don't Start Now" (2019) as a prize.

[7] She is occasionally affectionately referred to as Dula Peep by fans, which originated as a mispronunciation by American talk show host Wendy Williams in 2018.