While attending Mount Ayr High School, Miller participated in a number of sports, receiving a total of 15 letters in football, track and field, baseball and basketball.
In his senior year (1966), he was named to the Iowa All-State Football Team and set the Drake Relays High School Division record in long jump.
[1] In 1969, Drake's home game against Northern Iowa was designated as 'Duane Miller Day' and included a ceremony at halftime.
Although Drake lost 29- 21, Miller played an outstanding game, with 9 receptions for a total of 192 yards.
Duane Miller was the 5th player selection of the New York Giants in the 1970 NFL draft.
Miller played in all four preseason games and earned a spot on the regular season 53-man squad.