[2] Among those connected with the school were Philip Amelio, a former child actor, who once taught English and coached baseball.

Duanesburg high has teams in baseball, basketball, bowling, cheerleading, cross country, golf, soccer, softball, track and field, volleyball and wrestling.

[11] In late February 2011, Duanesburg senior wrestler Nick Gwiazdowski was named the Times Union "athlete of the week" for his two straight state Division II titles at the 215 pounds class.

[13] Gwiazdowski was the "dominant" wrestler at the New York state finals for the 2010-2011 academic year at the Times Union Arena.

Philip Amelio, a retired child actor, once taught English and coached baseball at Duanesburg High School.