By 1903, seventy five years after its founding, the Dublin Mission had eleven full-time missionaries under the leadership of Rev.
In December 1939, the Mission once again relocated to newly built headquarters in Cashel Road, Crumlin, an area which had grown to some 13,000 residents in the past thirty years.
This area was chosen because the Dublin Corporation had built almost 4,000 houses for working-class families nearby.
Another factor came from a fall in attendance at the location at Anglesea Street as people migrated from the centre of the city.
The mission runs a cafe for homeless people, a drop-in centre, youth services and a summer camp.