[4] The first Scramblers (1962–1967) were derived from street-legal models, and featured "narrow case" engines with lightly altered frames.

It originally derived from a Ducati Diana road bike converted by Michael Berliner for dirt-track racing in America.

[5] These Scrambler models all had a maximum engine capacity of 250cc, and are generally referred to as "narrow case Scrambler(s)" The second series used a wider engine case.

Frames were modified with experience derived from Bruno Spaggiari's Ducati factory racing motorcycles.

[6] The Scrambler name is revived in 2015 as Ducati's modern-classic styled motorcycle.