A French privateer captured her in September 1797 after she had delivered her captives on her sixth voyage.

Duke of Buccleugh first appeared in Lloyd's Register (LR) in 1784 with J.Ritchie, master, Thompson, owner, and trade London–New York.

After acquiring slaves in West Africa, Duke of Buccleugh arrived at Kingston on 1 June 1790 with 348 captives.

Duke of Buccleugh sailed to Bance Island where she started acquiring captives on 1 June.

She was also carrying as passengers Dr. Alexander Falconbridge, his wife Anna Maria, and brother William, of the Clapham Sect and the Anti-Slavery Society, who had come out with the intent of reorganising the failed settlement of freed slaves in Granville Town, Sierra Leone.

Duke of Buccleugh started gathering captives at Bance Island on 2 October.

Duke of Buccleugh was at Bance Island when on 18 September 1794 a French naval squadron comprising the razee Experiment under the command of lieutenant de vaisseau Arnaud, Vigilance, Félicité, Pervie, and Mutine arrived.

They were cruising the West African coast, destroying British factories and shipping.

[11] Only Duke of Buccleuch and Ann Philippa, of Liverpool, Lovelace, master, escaped.

[16] 6th enslaving voyage (1796–1797): Captain George Cleland acquired a letter of marque on 17 September 1796.

[18] On 6 September 1797, Duke of Buccleugh was homeward bound when she was captured and taken into Santiago de Cuba.