Counts and dukes of Guise

The Dukes of Guise and their sons played a prominent role in the French Wars of Religion, during which they were the leaders of the ultra-Catholic faction.

On the extinction of the Bourbon-Condé family in 1830, the Guise dukedom was inherited by the House of Orléans, descendants of Anne's granddaughter Louise Henriette de Bourbon, Duchess of Orleans.

The House of Luxembourg had disputed the countship of Guise, and with the approval of John, Duke of Bedford, English Regent of France, seized the county in 1425.

The marriage of Charles of Le Maine, younger brother of René, to Isabelle of Luxembourg, sister of Louis, allowed him to peacefully recover Guise.

This was undone by the Parlement of Paris at the request of other claimants to the estate, among whom was the wife of France's premier prince du sang Anne Henriette of Bavaria, Princess of Condé, a great-granddaughter of Charles of Lorraine, Duke of Mayenne through her mother.