He is the accordionist and vocalist for his New Orleans-based band, Dwayne Dopsie and the Zydeco Hellraisers.

[1] He is the youngest of accordionist Rockin' Dopsie's eight children, and picked up music in the household from an early age.

He began playing washboard at age six and accordion at seven, and performed with his father on stage at Mardi Gras and on television for a Super Bowl halftime during his childhood.

Dopsie plays regularly at New Orleans events such as Mardi Gras and Jazz & Heritage Festival, has done numerous tours of the United States,[6][7][8][9] and has toured internationally several times, including performances in Canada, Georgia, and China.

[4] In 2018, Dopsie signed with Louisiana Red Hot Records[permanent dead link‍], who released Bon Ton in the June, 2019.