[citation needed] He was a 4A All-State selection, leading Tucker to a 10–1 record his senior year.

As a redshirt freshman, he played in all 13 games and was named to the conference's all freshmen team as a punt returner.

East Carolina University won the 2007 Hawaii Bowl against Boise State on a team that also featured future NFL running back, Chris Johnson.

Regardless of his injury, East Carolina University won the 2008 Conference USA Championship against Tulsa.

[3] In his junior year, he was named to the Conference USA first-team and as the C-USA Special Teams Player-of-the-Year.

He played in all 14 games, including a victory against Houston in the 2009 C-USA Championship and a loss to Arkansas in the 2010 Liberty Bowl.

[4][5] In his senior year, Harris played in all 13 games and won the C-USA MVP award.

[7] Harris was selected by the Dallas Cowboys in the sixth round with the 176th overall pick in the 2011 NFL draft.

[12] His 78-yard return broke a fourth-quarter tie and earned him NFC Special Teams Player of the Week honors.

[13] His impact as a returner in special teams convinced the coaching staff to give him more opportunities at wide receiver.

Despite being active all season, it was not until week 12 against the Washington Redskins on Thanksgiving that he started to produce as a receiver, catching four passes for 71 yards.

[25] On March 10, 2015, he signed a five-year, $17 million contract with the New York Giants as an unrestricted free agent.

[37] On March 21, 2017, he restructured his contract after the Giants signed free agent wide receiver Brandon Marshall.

[38] In Week 5 of the 2017 season, Harris suffered a foot fracture which required surgery, and was placed on injured reserve on October 9, 2017.

[54] In the Bears' week 10 home loss to the Minnesota Vikings, Harris tore his triceps after he muffed a punt and attempted to recover it.