[3] On October 1, 2017, Cole recorded his first NFL interception and returned it for a touchdown in a 57–14 home win over the Tennessee Titans.
[4] On October 15, 2017, Cole made his second career interception in the game against the Cleveland Browns.
[5] On September 25, 2018, Cole was placed on injured reserve after playing through a dislocated wrist in Week 3 against the New York Giants.
[15][16] Cole was elevated to the active roster for the Titans Week 10 matchup with the New Orleans Saints.
On the kickoff to open the second half, Cole caused a fumble which resulted in a recovery for the Titans.