[2] Frittelli played college golf at the University of Texas, where he won the decisive match to lead his team to victory at the 2012 NCAA Championship.

Frittelli turned professional after the 2012 NCAA Championship and played on the European Tour via sponsors exemptions for the rest of the year.

In 2017 a tie for second place in the Eye of Africa PGA Championship and a playoff defeat in the Volvo China Open lifted Frittelli into the world top-100 for the first time.

At the end of the season he was runner-up in the Turkish Airlines Open and tied for 4th in the end-of-season DP World Tour Championship, Dubai, both Rolex Series events.

Frittelli won the AfrAsia Bank Mauritius Open in December 2017 beating Arjun Atwal at the first hole of a playoff.