It starts from Seleznyov Street and runs northeast, crosses Koshurnikov, Krasin, Shakespeare, Korolyov, Volochayevskaya and Polzunov streets.

The prospekt ends near the bridge over the Kamenka River.

Dzerzhinsky Prospekt is one of the oldest roads in Novosibirsk.

In the 17th and 18th centuries this road was part of Kalmyk Route which ran from Krivoshchyokovo (current Leninsky District of Novosibirsk) to Tomsk.

[2] Entrance to Beryozovaya Roshcha Station is located between Dzerzhinsky Prospekt and Koshurnikov Street.