The Electronic Entertainment Experience 2021 (E3 2021) was the 26th and final E3, during which hardware manufacturers, software developers, and publishers from the video game industry presented new and upcoming products.

[1][2][3] Virtual events included keynote sessions from major publishers broadcast from a live stage in Los Angeles, an awards show, and a preview night, as well as helping companies to hold online private meetings with media and businesses.

[4] Greg Miller, Jacki Jing, and Alex "Goldenboy" Mendez served as hosts of the virtual events.

The ESA had intended to hold an in person event in 2021 during its normal June dates, as stated to partners in April 2020, but had to alter their plans due to ongoing COVID-19 concerns.

[15] Companies that participated at the event included Nintendo, Microsoft, Capcom, Ubisoft, Take-Two Interactive, Warner Bros. Interactive Entertainment, Koch Media, Square Enix, Sega, Gearbox Software, Bandai Namco Entertainment, Turtle Beach, Verizon, and Xseed Games.

[16][17][18] Konami had planned to participate but announced later they would not be ready to present at E3 as they were deep into development on several projects which they would reveal at a later time.

The app and portal were used for accessing game showcases, developer panels, and press conferences, with some of this content also mirrored onto streaming services.

[22] Games covered during the event included Tom Clancy's Rainbow Six Extraction, Rocksmith+, Riders Republic, Tom Clancy's Rainbow Six: Siege, Assassin's Creed: Valhalla, Just Dance 2022, Far Cry 6, Mario + Rabbids Sparks of Hope, and Avatar: Frontiers of Pandora.

PDT., providing more info on Tiny Tina's Wonderlands, Godfall, Homeworld 3, Tribes of Midgard and a look at the Borderlands film.

2, Back 4 Blood, Contraband, Sea of Thieves, Battlefield 2042, 12 Minutes, Psychonauts 2, Fallout 76, The Elder Scrolls Online, Party Animals, Hades, Somerville, Halo Infinite, Diablo II Resurrected, A Plague's Tale: Requiem, Far Cry 6, Slime Rancher 2, Atomic Heart, Replaced, Grounded, Among Us, Eiyuden Chronicle: Hundred Heroes, The Ascent, The Outer Worlds 2, Microsoft Flight Simulator, Forza Horizon 5 and Redfall.

Ultimate, Life Is Strange, Life Is Strange: True Colors, Marvel's Guardians of the Galaxy, Worms Rumble, Astria Ascending, Two Point Campus, Super Monkey Ball: Banana Mania, Mario Party Superstars, Metroid Dread, Just Dance 2022, Cruis'n Blast, Dragon Ball Z: Kakarot, Mario Golf: Super Rush, Monster Hunter Stories 2: Wings of Ruin, WarioWare: Get It Together!, Shin Megami Tensei V, Danganronpa Decadance, Fatal Frame: Maiden of Black Water, Mario + Rabbids Sparks of Hope, Advance Wars 1+2: Re-Boot Camp, Hyrule Warriors: Age of Calamity, The Legend of Zelda: Skyward Sword HD, and the sequel to The Legend of Zelda: Breath of the Wild.

Among their picks, Forza Horizon 5 was named as the Most Anticipated Game overall, with the Microsoft and Bethesda event as the Best Presentation.

Geoff Keighley's second Summer Game Fest kicked off around the same time as E3 2021 and will last two months, through Gamescom in August 2021, featuring a range of promotional events outside of E3.

[50] Games presented included Shadow Warrior 3, Trek to Yomi, Phantom Abyss, Wizard With a Gun, Death's Door, Inscryption, Devolver Tumble Time, and Demon Throttle.

Games shown off in the event included:[63] GLITCH debuted its Future of Play Direct showcase on June 12, 2021.