Newer generations of Symmetrix brought additional host connection protocols which include ESCON, SCSI, Fibre Channel-based storage area networks (SANs), FICON and iSCSI.

The Direct Matrix Architecture (DMX) product line with models DMX800, DMX1000 and DMX2000 were announced in February 2003.

Each engine contains two director boards, memory chips, and front-end (FE) and back-end (BE) ports for connectivity to hosts and storage bays, respectively.

[4] The Symmetrix Remote Data Facility (SRDF) is a family of software products that facilitates the data replication from one Symmetrix storage array to another through a storage area network or Internet Protocol (IP) network.

An established pair of devices can be split, so that separate hosts can access the same data independently (maybe for backup), and then be resynchronised.