1FYJ, 4HVC, 4K86, 4K87, 4K88, 5A34, 5BMU, 5A1N, 5A5H2058107508ENSG00000136628ENSMUSG00000026615P07814Q8CGC7NM_004446NM_029735NM_001357474NP_004437NP_084011NP_001344403Bifunctional aminoacyl-tRNA synthetase is an enzyme that in humans is encoded by the EPRS gene.

[5][6] Alternative splicing has been observed for this gene, but the full-length nature and biological validity of the variant have not been determined.

[6] Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids.

The protein encoded by this gene is a multifunctional aminoacyl-tRNA synthetase that catalyzes the aminoacylation of glutamic acid and proline tRNA species.

[7] EPRS has been shown to interact with POU2F1,[8] Heat shock protein 90kDa alpha (cytosolic), member A1[9] and IARS.