ESN Vrilissia or ESN Vrilission (Greek: ΕΣΝ Βριλισσίων) is a Handball club that based in Vrilissia in the regional unit of North Athens, Attica.

The full name of club is Ekpolitistikos Syllogos Neon Vrilission (Greek: Εκπολιτιστικός Σύλλογος Νέων Βριλισσίων) that means Cultural Youth Association Vrilissia.

The club was founded in 1979 and has won one Greek Championship[1] and two Cups.

[2] In September 2011 the group was withdrawn by the first division championship (A1 Ethniki) because of financial difficulties.

[3] In current season the club plays in A2 Ethniki (second division).