Its human psychopharmacology was first described by Alexander Shulgin in the book TiHKAL.

On June 10, 2014, the UK Advisory Council on the Misuse of Drugs (ACMD) recommended that ETH-LAD be specifically named in the UK Misuse of Drugs Act as a class A drug despite not identifying it as ever having been sold or any harm associated with its use.

[3] The UK Home office accepted this advice and announced a ban of the substance to be enacted on 6 January 2015.

[5] Morning glory: Argyreia nervosa (Hawaiian Baby Woodrose), Ipomoea spp.

(Morning Glory, Tlitliltzin, Badoh Negro), Rivea corymbosa (Coaxihuitl, Ololiúqui)