Dwire acted for three years in stock theater with companies in Portland and Seattle.

[3] Dwire worked mainly as a villain in westerns,[citation needed] including Riders of Destiny (1933) with John Wayne in the first singing cowboy movie and The Trail Beyond (1934) opposite Wayne, Noah Beery, Sr., and Noah Beery, Jr.

He acted with John Wayne and Gabby Hayes in The Lawless Frontier (1934).

He also appeared in Bob Steele vehicles such as Alias John Law (1935).

He was a family friend of Bob Steele and his Dad, Robert North Bradbury.