[1] East Hagbourne's toponym is derived from Hacca's Brook, a stream that flows through the village.

Regenbald continued to hold the manor after the Norman conquest of England in 1066 and compilation of the Domesday Book in 1086.

Regenbald died in the reign of Henry I, who then granted East Hagbourne manor to the Augustinians of Cirencester Abbey (founded 1117).

The abbey continued to hold the manor until 1539, when it surrendered its lands to the Crown in the Dissolution of the Monasteries.

[2] On the floor of the north chapel are monumental brasses commemorating Claricia Wyndesor – quare fieri fecit istam capellam (why did he make this chapel) (died 1403) and her husband John York fundator istius Ile (founder of Ile) (died 1404).

[11] Tudor House, 46 Main Road, is a three-storey farmhouse with a thatched barn opposite the Village Cross.

[12] In the English Civil War in 1644, the Parliamentarian army billetted 6,000 horsemen in East Hagbourne.

A tiny window, only three inches square, in a house on Main Road, is said to have been used to spy on the Parliamentarian troops.

[14] On 10 March 1659 fire spread through the village, burning down a considerable number of thatched houses.

[16] Coscote Manor, about 1⁄2 mile (800 m) west of the village, is a timber-framed 17th-century house with fretwork bargeboards and an Ipswich window.

[2] For centuries Hagbourne parish extended north as far as the main road linking Wallingford and Wantage.

The Didcot, Newbury and Southampton Railway was built through the parish, passing west of the village & east of Coscote on the still extant Hagbourne Embankment – one of the line's most notable civil engineering features, built upon chalk dug from the route of the line through the Berkshire Downs.

[20] In 2015 Grainger plc proposed a high-density housing estate of 170 homes on land south of this new boundary.

[26] There is a small Post Office and a village shop in New Road, opened in 2001 and run by local volunteers.

In 2009 the village was one of nine UK finalists in the Royal Horticultural Society's Britain in Bloom competition.

These include an annual fun run on the May Day bank holiday, typically of 4+1⁄2 miles (7 km) to 5+1⁄2 miles (9 km), which involves a run around the surrounding area, including the villages of Blewbury and Upton.

There is an annual "scarecrow trail", a village fête and, in August, a duck race on Hacca's Brook.

In July 1975, the location scenes for the Doctor Who serial The Android Invasion were filmed in the village.

In 2015, two television channels featured East Hagbourne in reports about the Mind the Green Gap Campaign.