[4] Beginning in June 1941 the 34th Bomb Squadron, flying North American B-25 Mitchell bombers, was based at Pendleton.

It began flying anti-submarine patrols after the attack on Pearl Harbor in December 1941, and continued to do so until it moved to South Carolina in February 1942.

In the late 1960s and into the 1970s, United flew direct, no change of plane 727 service to Salt Lake City, Chicago, and Newark or Washington, DC (DCA).

In 1969 United 727-100s flew eastbound Portland - Pendleton - Boise - Salt Lake City - Chicago O'Hare Airport - Pittsburgh - Allentown/Bethlehem/Easton - New York Newark Airport and westbound Des Moines - Denver - Salt Lake City - Boise - Pendleton - Portland in addition to flying daily Boeing 737-200 service with a round trip routing of Pendleton - Portland - Eugene - Medford - San Francisco (SFO) for a total of three jet departures a day.

[8] In 1966 the airport was stop on a daily flight between Washington state and Oklahoma jointly operated by United and Continental Airlines as an interchange service with a Douglas DC-6B flying Seattle - Portland - Pendleton - Boise - Salt Lake City - Denver - Wichita - Tulsa while United was also operating twice daily round trip Portland - Pendleton - Spokane DC-6 service.

[12] By 1998, Horizon Air was operating four daily flights from Pendleton with de Havilland DHC-8 Dash 8 turboprop service to Portland.

Boutique Air has the option to operate trips from Pendleton to Boise, Idaho, but these will not be subsidized under the EAS program.