In late 2011, SeaPort began to reinvent its business model and the carrier ended its namesake route between Seattle (Boeing Field) and Portland on January 27, 2012.

As part of this business shift, on January 15, 2012, SeaPort Airlines began nonstop flights between Portland International Airport and North Bend/Coos Bay utilizing Cessna 208 Caravan single turboprop engine aircraft.

[11] As part of this growth SeaPort secured Department of Transportation approval to add daily flights between Kansas City International Airport and Harrison, Arkansas.

[13] In February 2013, SeaPort Airlines announced that its EAS contract for service to McKellar-Sipes Regional Airport in Jackson, Tennessee, had been extended by the U.S. Department of Transportation through January 31, 2014.

Following the 2014 phaseout of the Wright Amendment and the opening of a new terminal at Dallas Love Field, SeaPort had to share a single gate with Virgin America and lost its access to a permanent ticket counter; the resulting inconvenience and flight delays prompted SeaPort to transfer the Texas–Arkansas flights from Love Field to George Bush Intercontinental Airport in Houston in September 2015.

[14] On January 16, 2016, SeaPort ceased service to Salina, Great Bend, and Kansas City, citing a nationwide shortage of regional airline pilots.

The EAS contract was awarded to SeaPort in January 2013, replacing the incumbent carrier SkyWest Airlines, which linked Imperial to Los Angeles.