He is best known for his work with Hanna-Barbera Productions, where he helped design Fred Flintstone, Yogi Bear, and Huckleberry Hound.
Benedict began his animation career at Walt Disney Studios in 1930, and ultimately left three years later to work at Universal Studios as an animator on Walter Lantz Productions' Oswald the Lucky Rabbit shorts.
[1] Benedict left Hanna-Barbera in the late 1960s, but continued providing freelance work until his retirement in the early 1970s.
and as one of the advisors on Cartoon Network's original series Johnny Bravo in 1997, specifically a background consultant upon request by creator Van Partible whom was a huge fan of his work.
[4] He is cited as a major inspiration by animator John Kricfalusi (whom Ed worked for on A Day in the Life of Ranger Smith), among others.