After a brief spell as manager at Burnley, Howe returned to Bournemouth, and led them to two further promotions in three seasons, taking them to the top division of English football.

[6] After a year away from the game, Howe returned to management in 2021 when he was appointed as head coach of Newcastle United following the takeover of the club.

[7] Howe established himself as an important player in Bournemouth's defence, and in 1998, he was selected for the England Under-21 team in the Toulon Tournament.

He returned for the opening game of the 2002–03 season against Nottingham Forest, but he injured his knee again after only nine minutes[11] and was ruled out for the entire campaign.

[14] Despite the club's transfer embargo remaining in place for the rest of the season, Bournemouth secured promotion to League One after two years in the fourth tier of English football thanks to a 2–0 away win at Burton Albion on 24 April 2010.

[17][18] He took charge of his 100th and final Bournemouth match of his first managerial spell with the club, later that day in a 2–1 defeat away to Colchester United.

"[30] Bournemouth confirmed their promotion on the last day of the season, 2 May 2015, with a 3–0 victory at Charlton Athletic and, due to already-promoted Watford's failure to win their last match, were crowned champions of the league.

[31] Howe guided Bournemouth to Premier League survival in their first season in the top flight football, with a 16th-place finish seeing them five points clear of the relegation zone.

[38] Howe was appointed to replace Steve Bruce as the manager of Premier League club Newcastle United on 8 November 2021, signing a contract until the summer of 2024.

[39] Howe watched from the stands as the club drew 1–1 with Brighton & Hove Albion,[40] in a game in which Graeme Jones was acting as caretaker manager.

His appointment at Newcastle also reunited him with former players at Bournemouth, such as Callum Wilson, Matt Ritchie and Ryan Fraser.

[42] On 20 April 2022, following a 1–0 victory against Crystal Palace, Howe guided Newcastle to a sixth successive home win, the first time the club had achieved such a feat since 2004 under Sir Bobby Robson.

[49] On 6 January 2024, in the third round of FA Cup, in the 157th Tyne-Wear derby, Howe led Newcastle to victory over Sunderland, a 3–0 win at the Stadium of Light.

[50] Despite many injuries, Howe guided Newcastle to their highest ever scoring Premier League season with 85 goals scored and finished seventh;[51] losing out on a Europa Conference League qualification spot due to Manchester United beating Manchester City 2-1 in the 2024 FA Cup final.

[53] Howe completed his coaching badges with the Irish FA in 2011, implementing a tactically flexible system with the teams that he manages.

[54] Howe's coaching style has been influenced by such football managers as Jurgen Klopp, Johan Cruyff and Diego Simeone, having spent time observing the latter's training methods after leaving Bournemouth.