He played college football for the Alabama Crimson Tide, where he was a member of three BCS National Championship teams in the 2009, 2011, and 2012 seasons.

His family was forced to evacuate his childhood home due to Hurricane Katrina, fleeing to Beaumont, Texas to stay with Lacy’s aunt.

[3] In December 2008, he was selected by the Louisiana Sports Writers Association as a first-team player on the Class 5A All-State football team for the second consecutive season.

[4][5] Rated as the 13th best running back and the 116th best prospect overall by Rivals.com,[6] Lacy committed to the University of Alabama in February 2009.

[10] Lacy won three BCS National Championships with the Crimson Tide in his collegiate career.

[14] In the season opener against San Jose State, Lacy ran for 113 yards and two touchdowns in his collegiate debut.

[19][20] Aaron Suttles of The Tuscaloosa News wrote, "To the fans, Eddie Lacy is a dreadlocked blur, spinning past defenders into the secondary.

[28] He sustained a foot injury against SEC West rival Arkansas and did not play the following week against Vanderbilt.

[30] His average of 7.5 yards per carry ranked sixth among all players in the NCAA Division I Football Bowl Subdivision.

He had a career-high in rushing in a single game against the Chicago Bears, running for 150 yards on 22 carries with a 6.8 average.

[52] Lacy passed the 1,000-yd season mark on December 15 against the Dallas Cowboys when he ran for 141 yards and a touchdown on 21 carries.

[58] Lacy was selected as the 2013 Offensive Rookie of The Year, the first Packer chosen for the award since running back John Brockington in 1971.

[72] On September 20, he left Week 2's game against the Seattle Seahawks with an ankle injury and did not return.

"[74] On November 8, Lacy left during the 3rd quarter with a groin injury in Week 9's game against the Carolina Panthers.

[75] On November 10, the Packers declared Lacy inactive for Week 10's matchup against the Detroit Lions.

[76] On December 2, Lacy missed the Packers' team curfew and his status was impacted for Week 13's matchup against the Detroit Lions.

[79] The Packers made the playoffs and faced off against the Washington Redskins in the Wild Card Round.

[88][89] He was offered similar contracts from the Packers and Minnesota Vikings before ultimately choosing to sign with Seattle.

[92] On September 10, in his Seahawks debut, he had five rushes for three yards in a 17–9 loss to his former team, the Green Bay Packers.

[94] On September 30, 2024, Lacy was arrested in Scottsdale, Arizona on four charges, including suspicion of extreme DUI and possession of an open container inside a vehicle.