He rushed for 148 yards on 24 carries and scored twice in a 41–19 upset of C. J. Mosley's Theodore Bobcats in the first round of the playoffs.

Daphne finished the year with an unbeaten 15–0 record and the 2010 Alabama 6A State Championship, beating the defending champions Hoover Buccaneers, who were on a 21-game winning streak, in the final.

[6] Yeldon was also named a first-team All-State selection by the Alabama Sports Writers Association and second-team USA Today High School All-American.

At the prelims of the 2010 Lionell Newell Track Meet, he ran a career-best time of 11.35 seconds in the 100 meters, placing 12th overall in the finals.

[10] Understandably, he had scholarship offers from almost every football powerhouse, including Florida, Oregon, Penn State, and Tennessee.

[11] However, after the end of his senior season, he switched to Auburn's in-state rival Alabama, citing uncertainty over the Tigers' offensive coordinator position following Gus Malzahn's move to Arkansas State.

[17] In the 2013 BCS Championship Game victory over Notre Dame, Yeldon ran for 110 yards and had one touchdown.

[20] After Lacy entered the 2013 NFL draft, Yeldon became Alabama's starter his sophomore season in 2013.

[30] Jaguars head coach Gus Bradley named Yeldon the starting running back for the beginning of the season, ahead of veterans Denard Robinson, Toby Gerhart, and Bernard Pierce.

[31] On September 13, 2015, he made his NFL debut and carried the ball 15 times for 51 yards, while also catching three passes for 16-yards, in a 20–9 loss to the Carolina Panthers.

[34] After five consecutive starts to begin his rookie campaign, Yeldon missed the Week 6 matchup against the Houston Texans due to a groin injury.

[48] In the following game, a loss to the Kansas City Chiefs, he recorded 122 scrimmage yards and a receiving touchdown.

He and an inactive Fournette showed enough disinterest on the sideline that Jaguars Executive Vice President of Football Operations Tom Coughlin issued a statement calling the duo's behavior “disrespectful, selfish … unbecoming that of a professional football player.”[50] He finished the 2018 season with 104 carries for 414 rushing yards and one rushing touchdown to go along with 55 receptions for 487 receiving yards and four receiving touchdowns.