His biggest break came when he won the singing contest of Tawag ng Tanghalan, a popular TV variety show of the 60s and 70s.

Jukebox, the coin-operated machine which plays selected music, was said to have attained much popularity as well because of continuous requests of Peregrina's songs.

He was also the leading man in Dito sa Aking Puso (1970) with Nora Aunor and with Vilma Santos in Mardy.

Most of his films were produced by JBC Productions, which invariably paired him with Vilma Santos, Edgar Mortiz, Esperanza Fabon, and directed by Consuelo P. Osorio.

He died a month and a week later (April 30, 1977) at the age of 31 at Polymedic Hospital due to internal hemorrhage caused by the accident.